Industry Leaders
Who Trust Our Expertise

Onshape is the first and only full-cloud 3D CAD system that lets everyone on a design team work together using any web browser, phone, or tablet.

Onshape was built from scratch for the way today’s engineers, designers and manufacturers really work, giving them secure and simultaneous access to a single master version of their CAD data without the hassles of software licenses or copying files. Based in Cambridge, Massachusetts, Onshape is a new venture-backed company that includes key members of the original SolidWorks team plus elite engineers from the cloud, data security and mobile industries.

OPEN MIND Technologies AG develops and sells innovative CAD/CAM solutions that generate optimised NC milling and turning programs for machine tools from digital models.

Manufacturers from a broad range of industries around the globe have decided to go with OPEN MIND products because they enable cost-effective and efficient manufacturing. This leads to models, prototypes, tools, moulds, prismatic workpieces, integral components and more, all in impressive quality.

OPEN MIND is active in all of the important markets, such as Asia, Europe and North America, with international subsidiaries and a global network of sales partners. OPEN MIND Technologies AG is a Mensch und Maschine company.

Cloud-based BoM management tool for manufacturing companies & hardware startups. 

BoMs are the lifeblood of many engineering projects. For engineers, BoMs are either a tabular form in a drawing or a “miracle” inside PLM or ERP systems. BoMs usually end up as spreadsheets, however. We are taking BoM management to the cloud. Doing so enables the interlinking of BoMs making them shareable and reference-able in ways that transcends technical drawings. That will mean sharing purely tabular data with colleagues in procurement or linking BoM data to ERP or MRP systems. We see a lot of potential here. We formed Newman Cloud, Inc. to develop openBoM, a new and fresh approach using modern cloud tools and technologies to remove the pain of tracking BoM data spreadsheets across networks of engineers, supply chain managers, and contract manufacturers.

At Overcast Innovations, we’re redefining how ceilings are designed —transforming them from static features into strategic assets. Our premanufactured, modular cloud systems seamlessly integrate acoustics, lighting, and building technologies — delivering exceptional design flexibility while reducing cost, schedule, and environmental impact.

Overcast Clouds aren’t just ceilings — they’re complete, future-ready infrastructure platforms. By consolidating trades into a single, prefabricated installation, our systems typically reduce construction costs by 15% and compress installation timelines significantly. Plus, with adaptable panel designs, you gain the freedom to reconfigure your space over time without disruption.

Packsize is the global leader in On Demand Packaging^® for businesses with complex corrugated packaging.

This efficient and cost-effective, just-in-time packaging system and leading supply chain model resolves inventory and shipping complexities and delivers 11 benefits through a distinct mix of box making hardware, software, consumables, and services. Through a principal focus on right-sized and sustainable packaging created by Packsize, On Demand Packaging® provides customers the ability to create a custom-sized box for every order in their own facilities. This smart packaging process results in less waste, lower shipping costs, decreased damage rates, and increased customer satisfaction. Companies across a variety of industries have adopted On Demand Packaging® powered by Packsize, including fulfillment / e-commerce, furniture, cabinetry, printing / marketing, and manufacturing. Packsize has operations in more than 25 countries.

PARC is a renowned scientific research and Open Innovation company that's been at the heart of some of the most important technological breakthroughs of our time. We bring leading scientists, engineers and designers together to form teams across a series of Focus Areas that we believe are the future of technology, science and innovation.

Creativity and science are core to PARC's mission to reduce the time and risk attached to innovation. We draw on our revered history and our energy for the future to create technologies that improve our world and solve complex challenges.

Pelican Products, Inc. is the global leader in the design and manufacture of high-performance protective cases, temperature-controlled packaging solutions, advanced portable lighting systems and rugged gear for professionals and outdoor enthusiasts. Their products are used by professionals in the most demanding markets including fire safety, law enforcement, defense / military, aerospace, life sciences, industrial, entertainment, and in numerous outdoor markets. Pelican™ products are designed and built to last a lifetime. The company operates in 27 countries, with 23 international sales offices and eleven manufacturing facilities around the globe.

Determination and prediction of solubility, dissolution, permeability and human absorption is Pion’s core business. We screen and analyze pharmaceutical compounds using instrumentation, software and laboratory services.

Meeting the Challenge. Typically, a large pharmaceutical company will test over 3,000,000 molecules for activity. While about 30,000 "hits" may be discovered in a year, only about 30 candidate molecules reach the development stage. Finally only 3 molecules enter the market as drugs, and rarely are these "blockbusters". More often than not, only one molecule reaches consumers.

Drugability - Getting The Job Done. Active compounds often are rejected due to poor oral absorption pharmacokinetics: while they may perform well in a test tube, in the body they just can't reach their target sites. For example, the molecule may be just too insoluble in water, and like "brick dust" it is eliminated before it has a chance to interact. In order to reach a site of therapeutic action, a molecule has to traverse many barriers. These barriers are formed by cell membranes, composed of oily phospholipid bilayers, which block the passage of charged or hydrophilic molecules. If a molecule is highly charged, it will be highly soluble but then it will not pass these oily barriers. Other effects, such as metabolism and efflux will also limit absorption.

The Need for Better Prediction. Many candidate molecules fail because they cannot cross the phospholipid bilayer to reach their intended target. Laboratory test animals usually are not used during early screening for absorption efficiency. Although epithelial cell cultures such as Caco-2 are often used for this purpose, the tests are costly and require a licensing fee. There are much more effective approaches appropriate for early screening; absorption properties can be assessed by measuring the model-membrane bilayer permeability coefficient, the aqueous solubility and extent of retention by the membrane. This is often referred to as the acronym PSR (permeability-solubility-retention). 

For ionizable molecules, the PSR parameters are dependent upon pH. At a given pH, the PSR parameters indicate the charge state of a drug molecule and its solubility in water and membranes, which predict in vivo absorption into the circulatory system. PSR profiles are used to prioritize molecules for further study and to reject some molecules altogether.

Solutions. Pion offers a range of instruments and analytical services that improve lead generation, optimization and selection. All our solutions include API-sparing techniques designed to measure and predict the critical physicochemical properties of target molecules.

Since 1991, Prism Engineering has served as the Mid-Atlantic's predominant source for CAD/CAM solutions, expert level technical support, and award-winning training services. 

Having serviced thousands of design and manufacturing firms of all sizes and across many industries has uniquely positioned Prism at the forefront of leading technology suppliers throughout the nation. This status has earned Prism the advantage of representing only the best and most widely recognized CAD/CAM software and hardware products in the world.

Our team of dedicated support technicians, engineers, machinists and trainers, coupled with our vast array of support and certified training programs, assure the maximum return on your investment in today's powerful CAD/CAM Technology.

Call us today to learn how thousands of design and manufacturing professionals throughout the country are already benefiting from Prism's award winning technology and training.

Prism Engineering adheres to these Core Values:

• Relationships - Everyday our goal is to build and maintain relationships with our customers, suppliers, and co-workers to create a "customer for life" environment
• Profitable Growth - To realize profitable growth through operational excellence
• Work Ethic - We value the moral virtues of hard work, diligence, accountability, and integrity
• Teamwork - We believe in teamwork and the unlimited possibilities of collaborative energy
• Communication -  We support and encourage open communication and meaningful cooperation among colleagues and customers while striving to be the best at what we do - both as a company and individually

P&G is an international company reaching out to almost the entire world population with about 300 brands in 140 countries. Many of these world brands have become famous household names and are found in almost every home. 

Headquartered in Cincinnati - Ohio in the USA, P&G has local operations across the globe in more than 80 different countries, including numerous manufacturing sites and research & development technical centers. P&G is an internationally owned company with publicly traded shares, currently owned by over one million shareholders from around the globe.

The Company employs over 100 thousand people of different nationalities spread between North America, Latin America, Europe, Middle East, Africa and Asia. Diversity (of gender, race, religion, culture) is one of most important P&G assets in achieving their mission to understand and serve consumers round the world.

Since 1985, PTC has serviced top-notch customers, acquired key companies and created industry-leading products to help you achieve sustained product and service advantage.

Our technology solutions transform the way you create and service your products across the entire product lifecycle — from conception and design to sourcing and service.

PTC transforms the way you create, connect, operate and service smart things and systems through the combination of our process know-how and best of breed capabilities, all delivered through a flexible platform. Our solutions for Computer Aided Design (CAD), Product Lifecycle Management (PLM), Application Lifecycle Management (ALM), Service Lifecycle Management (SLM), and Internet of Things (IoT) enable process transformation and new sources of innovation for products and services that are increasingly smart and connected.

ThingWorx, the centerpiece of PTC’s IoT technology portfolio, combines capabilities from PTC Axeda solutions to deliver the world’s first complete IoT Platform, which includes connectivity, device cloud, business logic, big data analytics and remote service applications. The combination delivers a disruptive suite of technology that enables companies to securely connect smart things, quickly create applications, and ultimately transform the value chain.

Ramboll is a leading engineering, design and consultancy company founded in Denmark in 1945. The company employs more than 15,000 experts globally and has especially strong representation in the Nordics, UK, North America, Continental Europe, Middle East and Asia-Pacific. With 300 offices in 35 countries, Ramboll combines local experience with a global knowledgebase constantly striving to achieve inspiring and exacting solutions that make a genuine difference to our clients, the end-users, and society at large. Ramboll works across the following markets: Buildings, Transport, Planning & Urban Design, Water, Environment & Health, Energy and Management Consulting.